Dr. Linda Rubinstein

Affiliates
Telephone
Email
linda.rubinstein@gmail.com
    CV

    Position- Principal Investigator, Director of Research, The Joseph Sagol Neuroscience Center

    Summary

    Dr. Rubinstein’s lab aims to elucidate how environmental stressors and aging affect the brain and behavior. We use cutting edge behavioral and molecular methods to illuminate redox and immune dys-homeostasis in neurodegenerative disorders and in aging. We are particularly interested to uncover sex differences in neurodegeneration and neuro-inflammation. By combining behavioral cues and molecular markers, we aim to find early biomarkers predicting neuropathology. We work with in vivo transgenic animal models, as well as in vitro models, we also use extreme environments as a model for accelerated aging. Our research is relevant to neuroinflammatory pathologies including cancer, inflammaging, Alzheimer’s, Parkinson’s, ALS, MS, and depression.

    Overall, our research aims to advance more inclusive predictive and personalized medicine.

    Education

    INSTITUTION AND LOCATION

    DEGREE

    FIELD OF STUDY

     

    NASA Ames Research Center,

    Mountain View, California

    postdoc

    Neurobiology, Behavior,               Sex differences, Astrobiology, Translational physiology

    UC Berkeley, Berkeley California

    postdoc

    Biochemistry, Genetics

    Tel Aviv University, Tel Aviv, Israel

    Ph.D.

    Microbiology,

    Molecular Biology Genetics

    Hebrew University, Jerusalem,

    Israel

    M.Sc.

    Summa cum laude

    Medical Science, Physiology

    Hebrew University, Jerusalem,

    Israel

    B.Sc.

    Biology

     

    Affiliations

    *The Joseph Sagol Neuroscience Research Center, Sheba

    *The Longevity Center, Sheba

    *The Multidisciplinary Gonda Brain Research Center, Bar Ilan

    Research Interests

    • Elucidate redox and immune dys-homeostasis in neurodegenerative diseases and in aging.
    • Find early biomarkers and behavioural cues for neurodegeneration.
    • Immune and redox modulation as a possible therapy for neurodegenerative pathologies
    • Sex-differences in neurodegeneration and neuro-inflammation
    • Underlying mechanisms of how environmental stressors affect brain and behaviour.
    • Using extreme environments (e.g. space) as a model for accelerated aging.
    • Space medicine, astrobiology, and space research
    Research

    Dr. Rubinstein’s lab aims to elucidate how environmental stressors and aging affect the brain and behavior. We use cutting edge behavioral and molecular methods to illuminate redox and immune dys-homeostasis in neurodegenerative disorders and in aging. We are particularly interested in uncovering sex differences in neurodegeneration and neuro-inflammation. By combining behavioral cues and molecular markers, we aim to find early biomarkers predicting neuropathology. We work with in vivo transgenic animal models, as well as in vitro models, we also use extreme environments as a model for accelerated aging. Our research is relevant to neuroinflammatory pathologies including cancer, inflammaging, Alzheimer’s, Parkinson’s, ALS, MS, and depression.

    Overall, our research aims to advance more inclusive predictive and personalized medicine.

    Lab SiteHTTPS://lab.Rubinste.in

    LinkedIn - https://www.linkedin.com/in/linda-rubinstein-74345a34/

    Publications (link to Google Scholar)

    https://scholar.google.com/citations?user=Jz380dkAAAAJ&hl=en       

    Publications

    Last Updated Date : 01/01/2024